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What Is Nexium (Esomeprazole) 20 mg?

Nexium (Esomeprazole) is a prescription medication that is used to treat gastroesophageal reflux disease (GERD) and Zollinger-Ellison syndrome, also known as gastroesophageal reflux disease and Zollinger-Ellison syndrome.

What is Nexium (Esomeprazole) used for?

Esomeprazole belongs to a group of medicines called proton pump inhibitors (PPIs). It works by reducing the amount of acid made in the stomach.

What is in Nexium (Esomeprazole)?

Nexium is an acid-suppressing medication that is used to treat gastroesophageal reflux disease (GERD) and Zollinger-Ellison syndrome, also known as gastroesophageal reflux disease and Zollinger-Ellison syndrome.

To find out more, talk about Nexium (Esomeprazole) as part of a comprehensive medical treatment plan.

Nexium is a prescription medication that is used to treat gastroesophageal reflux disease (GERD) and Zollinger-Ellison syndrome, also known as gastroesophageal reflux disease and Zollinger-Ellison syndrome).

While esomeprazole is known as an effective treatment for GERD and Zollinger-Ellison syndrome, there are a few things you should keep in mind when taking Nexium (Esomeprazole).

How does Nexium (Esomeprazole) work?

Esomeprazole (Nexium) works by reducing the amount of acid made in the stomach.

This occurs because hydroxy-ciclopropionic acid (H2-PABA) in the stomach causes the substance to move into the stomach and produce a disulfiram-like unpleasant effect called proton pump inhibitor (PPI).

Are there any side effects in taking Nexium (Esomeprazole)?

Like all medicines, Nexium (Esomeprazole) can have side effects. However, like all medicines, it can be taken to help minimize these. The most common side effects are headaches, heartburn, and upset stomach.

If any of these effects last or get worse, it’s important to talk to your doctor or pharmacist.

If any of these effects don’t go away, it's important to see a doctor or visit a specialist at a hospital.

What are the side effects of Nexium (Esomeprazole)?

Headache

The most common side effect of Nexium is headache. However, more severe headaches such as diarrhea, constipation, and difficulty sleeping are also known to occur. If you notice any of these symptoms, stop taking Nexium and call your doctor immediately or seek immediate medical attention.

Other less common side effects include vomiting, stomach pain, and difficulty breathing.

If you have any more serious side effects, it is important to talk to your doctor or specialist.

Heartburn

In rare cases, Nexium can cause heartburn in some people. It can also cause an increase in stomach acid levels.

Other less common side effects of Nexium include dry mouth, decreased vision, and increased heart rate.

Constipation

In some cases, Nexium can cause constipation or stomach pain. It can also affect how well you respond to other treatments.

Other less common side effects of Nexium include nausea, vomiting, stomach pain, and difficulty breathing.

Nausea

In some cases, Nexium can cause nausea.

Nexium® 24HR 20mg Mini Capsules provide lasting relief from frequent heartburn and acid reflux in a 53% smaller capsule (based on volume of the capsule vs Nexium® 24HR Once Daily Dosing Tablet)

Nexium 24 Hour Once Daily Dosing provides lasting relief for frequent heartburn & acid reflux.

Boxed Contents: 14 Mini Capsules Size: 14 Mini Capsules

Warnings

Do not use:

  • For children under 18 years of age.
  • If allergic to esomeprazole.
  • If allergic to any other proton pump inhibitor (omeprazole, rabeprazole, lansoprazole, pantoprazole).
  • If you are taking antiretroviral medicines, such as atazanavir.
  • If you are taking cilostazol, a medicine used to treat pain and/or cramping in the lower leg (or arms) due to inadequate blood flow to the muscles.
  • If you are breastfeeding or intend to breastfeed.
  • If the expiry date printed on the pack has passed.
  • Do not use if foil seal is broken.

CAUTION Always read the label. Follow the directions for use.

Ingredients

Each capsule contains Esomeprazole magnesium trihydrate 22.3mg (equivalent to esomeprazole 20mg)

Active Ingredients: Each capsule contains Esomeprazole magnesium trihydrate 22.3mg (equivalent to esomeprazole 20mg)

Directions

Adults 18 years, of age and over: Take 1 capsule daily for at least 7 days and up to 14 days.

Swallow the capsule whole with water, with or without food. Do not crush, chew or open the capsule. Not intended for immediate relief. It may take a few days to achieve maximum results.

Do not take for more than 14 days unless directed by a doctor.

USAGE ADVICE The bottle contains a sealed container with silica gel desiccant. Keep the bottle tightly closed to protect from moisture.

SAFETY DIRECTIONS

Carefully read the enclosed leaflet before use.

Ask your doctor or pharmacist before use if you:

  • Are pregnant or intend to become pregnant,
  • Have or ever have had serious liver disease.
  • Are taking digoxin (a medicine used to treat heart problems.
  • Are taking ketoconazole (a medicine used to treat fungal infections).
  • Are taking clopidogrel or warfarin (medicines used to stop the blood clotting).
  • Are taking other medicines regularly.

STORAGE INSTRUCTIONS Store below 25°C in a cool, dry place. Storage Temperature: Below 25°C.

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Do not take more than 1 capsule daily.

Always read the label. Storage Temperature: Below 25°C

USAGE ADMINISTRATION: Check the packaging for safety information. Use with caution if you have heartburn.

DOSAGE: Common usage may require a short course of treatment before the full effect is seen. If used twice daily, the perademic research group found no significant difference in overall patient pain or duration of treatment between Nexium 24HR and esomeprazole magnesium trihydrate capsules. However, the study authors suggest using a different capsule formulation for 24HR if esomeprazole magnesium trihydrate capsules are causing significant patient discomfort. However, the study authors cautioned that results should be interpreted in the context of clinical trial data, as they were conducted on a larger scale, and were not powered to detect a difference in pain or duration of treatment. Therefore, the decision to use esomeprazole magnesium trihydrate capsules should be based on a thorough assessment of the patient's specific needs, symptoms, and expectations. Additionally, individual reactions to treatment may vary, and the decision to use esomeprazole magnesium trihydrate capsules should be based on a decision to use esomeprazole magnesium trihydrate capsules in line with the doctor's instructions.

For external use only. Do not use if broken or crushed or used more than prescribed.

Product Name:Esomeprazole Nexium Tablets USP, 20 mg

Product Form: Tablets

Manufacturer:Pfizer, Inc.

Pack Size:5 x 10 tablets

Strength:20 mg

Product Description

Esomeprazole Nexium Tablets USP, 20 mg is a prescription medication for the treatment of frequent heartburn. It belongs to a class of drugs known as proton pump inhibitors. These tablets are a part of a class of drugs called a proton pump inhibitor. It works by reducing the amount of acid the stomach makes.

This product is not intended for women and should be used with caution in pregnant women and breastfeeding women.

Do not use if you have serious liver disease, if you have a stomach ulcer, if you have a history of gastrointestinal disease, if you have ever had jaundice or hepatic impairment.

If you are taking an anti-acid medication for heartburn, take it at least 2 hours before or after you reduce the amount of an acid-suppressing drug in your stomach.

If you have heartburn with a recent meal, take it at the same time each day.

Some patients find that taking these tablets causes more heartburn than others.

The active ingredient in these tablets is Esomeprazole.

It is not known if these tablets are safe and effective in women who are pregnant or may become pregnant.

Read the label carefully before you start taking this medicine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Always read the label. Use only as directed. If you have any questions, talk to your doctor or pharmacist. You should always speak to a healthcare professional who has experience with other drugs. Special attention is necessary in cases of overdose, use with caution, and in patients with a known hypersensitivity to the active ingredient.ossidias ReckittBenecoupling, Inc.

This product is not intended for women and should be used discretionally.

Read the package leaflet before you start taking this medication. This medicine is not a controlled substance.

Take this medicine in the dose and duration as advised by your doctor. Swallow the tablet promptly after ingestion. Do not take this medicine if it is taken with food or medicine. In either case, drink and eat the tablet immediately.

Do not take this medicine more often than once a day. For best results, take it in the evening before having a meal.

Avoid large or large meals that contain alcohol as it may delay the healing of the painful ulcers.

For best results, do not take this medicine with any of the following:

  • Amlodipineany medicines used to treat high blood pressure; potassium-sparing diuretics; and heart-dilating steroids. If you are using medications for this condition, always start with a lower dose and gradually increase your dose. If this medicine does not seem to help, your doctor may increase your dose to the lower limit.
  • Antidiarrhythmicsany medicines used to treat epilepsy or dementia.
  • Anticholinergic medicationsmedications used to treat swelling and irritation (such as spasms or hives) of the mouth or throat.
  • Anticholinococcal medicationsmedicines used to treat infections (such as colds or shingles).
  • Antihistaminesmedicines used to treat breathing problems (such as asthma or chronic obstructive pulmonary disease).
  • Antiviralsmedicines used to prevent pregnancy. Always start with a lower dose and gradually increase your dose. If this medicine does not help, you may need additional medicine, or you may need to use a different medicine.
  • Asthma medicationSome types of skin-related infections, such as colds and skin infections. Check with your doctor before you use these medicines.

March 2, 2015/PRNewswire/ -- Pharmaceutical Research and Manufacturers of America (PRA) today announced that the U. S. Food and Drug Administration (FDA) approved Nexium® (esomeprazole magnesium) 20 mg tablet to treat frequent heartburn, and a proton pump inhibitor called esomeprazole for gastroesophageal reflux disease (GERD) prevention in adults and children aged two years and over. The drug is indicated in adults and children as an adjunct to diet and exercise and may be used for patients with GERD who do not respond to standard dietary and exercise management. The FDA's approval will require approval by the end of 2012, and Nexium® will be available in the US market by year-end, subject to approval by the FDA.

About Nexium®

Nexium® is indicated for the treatment of frequent heartburn, and a proton pump inhibitor called esomeprazole for gastroesophageal reflux disease (GERD) prevention in adults and children aged two years and over. The drug is a proton pump inhibitor which reduces acid production in the stomach by inhibiting the acid production of certain types of gastric and esophageal tissues. In children aged two years and over, esomeprazole can be used to treat GERD. The drug is available in a generic form called Nexium® and is approved by the FDA for the treatment of GERD. Nexium® is used in adults and children aged 2 years and over. To learn more, visit http://www.nexium.com.